Gary K Schwartz Selected Research

Gastrointestinal Neoplasms (Gastrointestinal Cancer)

1/2009	90-kDa heat shock protein inhibition abrogates the topoisomerase I poison-induced G2/M checkpoint in p53-null tumor cells by depleting Chk1 and Wee1.
7/2005	Development of cell cycle active drugs for the treatment of gastrointestinal cancers: a new approach to cancer therapy.
12/2003	The cyclin-dependent kinase inhibitor flavopiridol potentiates gamma-irradiation-induced apoptosis in colon and gastric cancer cells.

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Gary K Schwartz Research Topics

Disease

116	Neoplasms (Cancer) 03/2024 - 02/2002
37	Sarcoma (Soft Tissue Sarcoma) 09/2023 - 04/2005
28	Uveal melanoma 01/2023 - 04/2011
26	Melanoma (Melanoma, Malignant) 10/2023 - 04/2010
16	Liposarcoma 01/2023 - 07/2007
12	Neoplasm Metastasis (Metastasis) 01/2023 - 12/2002
10	Fatigue 03/2024 - 05/2005
9	Neutropenia 01/2020 - 04/2002
7	Neurofibrosarcoma (MPNST) 10/2021 - 04/2008
7	Colonic Neoplasms (Colon Cancer) 03/2011 - 07/2002
6	Leiomyosarcoma 04/2024 - 11/2018
6	Synovial Sarcoma (Synovioma) 03/2024 - 09/2012
6	Diarrhea 03/2024 - 05/2005
6	Nausea 03/2024 - 10/2008
6	Breast Neoplasms (Breast Cancer) 01/2020 - 01/2007
6	Disease Progression 12/2018 - 11/2006
6	Colorectal Neoplasms (Colorectal Cancer) 11/2010 - 03/2004
4	Vomiting 03/2024 - 10/2008
4	Exanthema (Rash) 03/2024 - 04/2016
4	COVID-19 01/2023 - 10/2020
4	Polyploidy 03/2016 - 03/2009
3	Myxoid Liposarcoma 03/2024 - 01/2015
3	Fever (Fevers) 11/2022 - 01/2018
3	Carcinogenesis 02/2021 - 01/2009
3	Squamous Cell Carcinoma of Head and Neck 02/2021 - 02/2002
3	Ewing Sarcoma (Sarcoma, Ewing) 07/2020 - 12/2011
3	Hypertension (High Blood Pressure) 12/2018 - 11/2006
3	Carcinoma (Carcinomatosis) 04/2016 - 08/2005
3	Hemangiosarcoma (Angiosarcoma) 03/2015 - 07/2009
3	Stomach Neoplasms (Stomach Cancer) 04/2009 - 06/2003
3	Gastrointestinal Neoplasms (Gastrointestinal Cancer) 01/2009 - 12/2003
2	Edema (Dropsy) 03/2024 - 01/2018
2	Pain (Aches) 03/2024 - 01/2018
2	Hepatocellular Carcinoma (Hepatoma) 01/2024 - 11/2012
2	Lymphoma (Lymphomas) 01/2023 - 04/2013
2	Injection Site Reaction 11/2022 - 08/2010

Drug/Important Bio-Agent (IBA)

16	Irinotecan (Camptosar)FDA LinkGeneric 11/2012 - 07/2002
14	Phosphotransferases (Kinase)IBA 01/2024 - 12/2006
14	alvocidib (flavopiridol)IBA 11/2012 - 04/2002
12	DNA (Deoxyribonucleic Acid)IBA 12/2021 - 07/2005
11	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2022 - 04/2008
9	Dacarbazine (DIC)FDA LinkGeneric 04/2024 - 06/2014
9	Cyclin-Dependent Kinases (cdk Proteins)IBA 08/2023 - 04/2002
9	Proteins (Proteins, Gene)FDA Link 10/2020 - 04/2011
8	Imatinib Mesylate (Gleevec)FDA Link 11/2018 - 06/2006
8	AZD 6244IBA 01/2018 - 01/2012
6	Sorafenib (BAY 43-9006)FDA Link 01/2024 - 08/2007
6	Temozolomide (Temodar)FDA LinkGeneric 01/2023 - 04/2013
6	Mitogen-Activated Protein KinasesIBA 01/2022 - 04/2008
6	palbociclibIBA 01/2020 - 01/2012
5	Immune Checkpoint InhibitorsIBA 10/2023 - 10/2018
5	Biomarkers (Surrogate Marker)IBA 01/2023 - 11/2011
5	GTP-Binding Proteins (G-Protein)IBA 01/2023 - 07/2012
5	Protein Kinase CIBA 01/2022 - 03/2005
5	Sirolimus (Rapamycin)FDA Link 10/2021 - 10/2010
5	IpilimumabIBA 01/2018 - 04/2010
5	Docetaxel (Taxotere)FDA Link 03/2016 - 06/2003
5	Fluorouracil (Carac)FDA LinkGeneric 12/2009 - 03/2004
4	RNA (Ribonucleic Acid)IBA 10/2023 - 08/2015
4	tyrosine receptor (receptor, tyrosine)IBA 01/2023 - 01/2016
4	sotrastaurinIBA 01/2022 - 05/2014
4	Paclitaxel (Taxol)FDA LinkGeneric 01/2021 - 04/2002
4	Adenosine Triphosphate (ATP)IBA 09/2017 - 01/2012
4	Cyclin-Dependent Kinase 4IBA 01/2017 - 01/2012
4	Doxorubicin (Adriamycin)FDA LinkGeneric 07/2016 - 10/2005
4	Small Interfering RNA (siRNA)IBA 01/2015 - 04/2009
4	Checkpoint Kinase 1IBA 09/2014 - 04/2007
4	2- ((3- ((4- ((5- (2- ((3- fluorophenyl)amino)- 2- oxoethyl)- 1H- pyrazol- 3- yl)amino)quinazolin- 7- yl)oxy)propyl)(ethyl)amino)ethyl dihydrogen phosphateIBA 04/2013 - 03/2009
3	Ifosfamide FDA LinkGeneric 03/2024 - 01/2009
3	AnthracyclinesIBA 03/2024 - 03/2016
3	Antineoplastic Agents (Antineoplastics)IBA 01/2023 - 07/2010
3	ErbB Receptors (EGF Receptor)IBA 12/2022 - 03/2005
3	AntibodiesIBA 11/2022 - 02/2018
3	CrizotinibIBA 01/2022 - 12/2013
3	selinexorIBA 01/2022 - 10/2016
3	Aspartate Aminotransferases (Aspartate Transaminase)IBA 10/2021 - 11/2015
3	Alanine Transaminase (SGPT)IBA 10/2021 - 11/2015
3	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 01/2021 - 02/2002
3	TensinsIBA 10/2020 - 04/2011
3	IGF Type 1 Receptor (IGF 1 Receptor)IBA 07/2020 - 04/2011
3	Retinoblastoma ProteinIBA 01/2020 - 01/2012
3	AntigensIBA 10/2018 - 01/2013
3	TOR Serine-Threonine KinasesIBA 09/2017 - 01/2012
3	Insulin-Like PeptidesIBA 04/2016 - 04/2011
3	TrabectedinIBA 03/2016 - 01/2015
3	Gemcitabine FDA Link 03/2016 - 01/2015
3	Bevacizumab (Avastin)FDA Link 01/2015 - 10/2005
3	Cisplatin (Platino)FDA LinkGeneric 04/2011 - 11/2006
3	PoisonsIBA 01/2009 - 09/2004
3	Type I DNA Topoisomerases (Topoisomerase I)IBA 01/2009 - 09/2004
2	T-Cell Antigen Receptors (T-Cell Receptor)IBA 03/2024 - 10/2018
2	NivolumabIBA 10/2023 - 01/2018
2	olaparibIBA 01/2023 - 12/2020
2	Complement System Proteins (Complement)IBA 01/2023 - 01/2023
2	sitravatinibIBA 01/2023 - 01/2016
2	VaccinesIBA 11/2022 - 10/2018

Therapy/Procedure

72	Therapeutics 03/2024 - 12/2002
35	Drug Therapy (Chemotherapy) 03/2024 - 12/2002
7	Immunotherapy 01/2023 - 05/2013
4	Radiotherapy 12/2021 - 12/2002